Multiple Myeloma Symptoms Rash
Multiple myeloma symptoms rash – Multiple myelomas is a type of cancer that affects the bone marrow, the training system of the blood of the organism. The plasma cells (a type of white blood cell) become abnormal and multiply rapidly, which hinders the production of normal blood cells. The excessive growth of malignant cells in the bone marrow can also weaken the bones, especially in the back and ribs, with the onset of pain and bone fractures.
Multiple Myeloma Symptoms Rash
Multiple myelomas are uncommon, in Spain today there are about 10000 cases every year are diagnosed 2000 more. Although it is unknown the exact cause, multiple myeloma can be controlled in most patients, sometimes for many years. The development of drugs novel has helped to control the multiple myeloma in a larger number of patients and has been associated with increased survival. See Also: Causes of Multiple Myeloma.
Multiple myeloma symptoms rash – Patients with myeloma may be asymptomatic with an increase in proteins that cannot be explained in the blood. Patients diagnosed with multiple myeloma does not usually manifest symptoms in the early stages of the disease. The signs to be alert for include:
- Fatigue: since the cells myelomatosis move to the other blood cells in the bone marrow, decreases the number of red blood cells in the body. This gives rise to the symptoms of tiredness.
- Bone pain: it is especially frequent in the dorsal region or lumbar spine, the ribcage and the hips. The pain can be mild or intense depending on the size of the lesion, the speed with which it has developed and if there has been a fracture or nerve compression. Normally, the movement becomes much worse the pain.
- Infection: since the cells myelomatosis displaces normal white blood cells, which fight infection, there is a risk of infection. The symptoms of infection depend on the location of the same. Pneumonia, infections of bladder or kidney, sinus and skin infections are frequent.
- Hypercalcemia: the presence of a high amount of calcium in the bloodstream. When you destroy the bone, calcium is released into the blood circulation. As you increase the amount, the kidneys are not able to get rid of the calcium in the urine. Symptoms of hypercalcemia consist of thirst, nausea, constipation, and mental confusion.
- The presence of one or more of the symptoms cited does not necessarily imply that you have multiple myeloma. However, it is important that you see these symptoms to your doctor, since they may indicate other health problems.
- Fractures: bone damage is the most serious problem when it is diagnosed myeloma. It is because the cells myelomatosis produce substances called cytokines, which can make the bone cells (osteoclasts) to destroy the adjacent bone. When it has been destroyed more than 30% of the bone, the x-rays show a thinning of the bone (osteoporosis) or the presence of holes dark (lytic lesions). The weakened area of bone can break, which is known as a pathological fracture. To prevent bone destruction, the doctor may recommend the administration of drugs that prevent osteoclasts from destroying the bone.
It’s a blood disorder, usually arising in the bone marrow and is closely associated with lymphoma and leukemia. Effective myeloma treatment for today does not exist, therapy is aimed at slowing disease progression.
In myeloma, a certain kind of white blood cells called plasma begins to multiply abnormally in the bone marrow. Plasma cells are responsible for producing antibodies that help the body fight off infections. When myeloma such cells isolated in bone and blood harmful protein called immunoglobulin, which gradually accumulates in the body. Multiple myeloma symptoms rash – Inside the bone marrow, the myeloma cells secrete chemicals into the plasma, which leads to weakening and bone fractures. With the development of myeloma the blood of pathogenic cells spread to other parts of the body.